A very warm welcome to our latest edition of labCrystal. This edition presents studies across a diverse range of research areas in which protein crystallography is having an impact, such as drug discovery, cell biology of flies and infectious diseases...
- an innovative fragment screening strategy from KU Leven for allosteric drug binding
- how low-volume, high-throughput crystal soaking for protein-ligand complexes enabled the AstraZeneca team to screen a fragment-based lead generation library
- a joint study on low volume crystallisation and optimisation provided the teams from the University of California and University of Texas to gain insights into the induction and response of the KstR protein from M. tuberculosis
- initial screening and optimisation of Ana2 crystal formation by assembling centriole cartwheels in flies from Oxford University
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